PPM1A Polyclonal Antibody

Background:
PPM1A(Protein phosphatase 1A) is also named as PPPM1A and belongs to the PP2C family. It is a serine/threonine protein phosphatase that is essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and that it negatively controls many signaling pathways which are critical for trophoblast invasion.(PMID:19404668). This protein distributes in both the cytoplasm and nucleus of mammalian cells(PMID:9003755). It has 2 isoforms produced by alternative splicing.

Research Area: Signal Transduction

Synonyms:
Protein phosphatase 2C isoform alpha , EC 3.1.3.16 , FLJ42306 , IA , MGC9201 , Mpp alpha , PP2C alpha , PP2C-alpha , PP2CA , PP2Calpha , PPM 1A , PPM1A , PPPM1A , Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform , Protein phosphatase 1A , Protein phosphatase 1A magnesium dependent alpha , Protein phosphatase 2C alpha , Protein phosphatase 2C alpha isoform , Protein phosphatase 2C isoform alpha , Protein phosphatase IA , Protein phosphatase, Mg2+/Mn2+ dependent 1A

Immunogen: Recombinant Mouse Protein phosphatase 1A protein

Swissprot: P49443

Calculated MW: 42 kDa
Observed MW: 42 kDa

Purification Method: Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.