PPM1B Polyclonal Antibody

Background:
protein phosphatase, Mg2+/Mn2+ dependent 1B(PPM1B) Homo sapiens The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008],

Immunogen: Synthesized peptide derived from human protein . at AA range: 310-390

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 52

GeneID: PPM1B PP2CB

Storage: -20°C/1 year

NOTE: For Research Use Only