PPOX polyclonal, anti-human, mouse, rat

Background:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Synonyms: PPO, V290M, VP

Cellular Location: Intermembrane side Mitochondrion inner membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human PPOX

Gene Symbol: PPOX

Gene ID: 5498

Swiss prot: P50336

Calculated MW: 51kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.