PPOX Polyclonal Antibody

Background:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Tags and Cell markers

Synonyms:
MGC8485, PPO, PPOX, PPOX, Protoporphyrinogen oxidase, V290M, Variegate porphyria, VP

Immunogen: Synthetic peptide of human PPOX

Swissprot: P50336
Gene Accession: NP_000300

Calculated MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32363/sc-32364/sc-67040