PPOX Polyclonal Antibody

Background:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Tags and Cell Markers

Synonyms:
MGC8485, PPO, PPOX, PPOX, Protoporphyrinogen oxidase, V290M, Variegate porphyria, VP

Immunogen: Fusion protein of human PPOX

Swissprot: P50336
Gene Accession: BC002357

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.54 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.