PPOX Polyclonal Antibody

Background:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Tags and Cell Markers

Synonyms:
PPOX, PPO, V290M, VP

Immunogen: Recombinant fusion protein of human PPOX (NP_001116236.1).

Swissprot: P50336
Gene ID: 5498

Calculated MW: 50 kDa
Observed MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.