PPP1A (clone 1H1-F7-D8), anti-human

Background:
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: PP-1A, PP1A, PP1alpha, PPP1A

Cellular Location: Cytoplasm Nucleus nucleolus nucleoplasm

Immunogen:
Purified recombinant human PPP1A protein fragments expressed in E.coli.

Gene Symbol: PPP1A

Gene ID: 5499

Swiss prot: P62136

Calculated MW: 37kDa

Recommended dilution:
WB 1:1000, IHC 1:50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.