PPP1CA Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13424a
Background:
The protein encoded by this gene is one of the threecatalytic subunits of protein phosphatase 1 (PP1). PP1 is aserine/threonine specific protein phosphatase known to be involvedin the regulation of a variety of cellular processes, such as celldivision, glycogen metabolism, muscle contractility, proteinsynthesis, and HIV-1 viral transcription. Increased PP1 activityhas been observed in the end stage of heart failure. Studies inboth human and mice suggest that PP1 is an important regulator ofcardiac function. Mouse studies also suggest that PP1 functions asa suppressor of learning and memory. Three alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.
Other Names:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13424a was selected from the N-term region of PPP1CA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PPP1CA
Gene ID: 5499
Primary Accession: P62136
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is one of the threecatalytic subunits of protein phosphatase 1 (PP1). PP1 is aserine/threonine specific protein phosphatase known to be involvedin the regulation of a variety of cellular processes, such as celldivision, glycogen metabolism, muscle contractility, proteinsynthesis, and HIV-1 viral transcription. Increased PP1 activityhas been observed in the end stage of heart failure. Studies inboth human and mice suggest that PP1 is an important regulator ofcardiac function. Mouse studies also suggest that PP1 functions asa suppressor of learning and memory. Three alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.
Other Names:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13424a was selected from the N-term region of PPP1CA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PPP1CA
Gene ID: 5499
Primary Accession: P62136
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review