PPP1CB Polyclonal Antibody

Background:
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD, NSLH2

Immunogen: Recombinant fusion protein of human PPP1CB (NP_002700.1).

Swissprot: P62140
Gene ID: 5500

Calculated MW: 37 kDa
Observed MW: 30-35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.