PPP1R15A Polyclonal Antibody

Background:
PPP1R15A (Protein Phosphatase 1 Regulatory Subunit 15A) is a Protein Coding gene. Diseases associated with PPP1R15A include Malignant Pleural Mesothelioma. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Activation of cAMP-Dependent PKA. GO annotations related to this gene include protein kinase binding.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
Apoptosis associated protein, GADD 34, Growth arrest and DNA damage inducible 34, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, Ppp1r15a, PR15A, Protein phosphatase 1 regulatory (inhibitor) subunit 15A, Protein phosphatase 1 regulatory subunit 15A

Immunogen: Synthetic peptide of human PPP1R15A

Swissprot: O75807
Gene Accession: NP055145

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.8 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:2000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.