PPP1R1A Polyclonal Antibody

Background:
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
I 1, I-1, I1, Inhibitor 1, IPP 1, IPP-1, IPP1, Ppp1r1a, PPR1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1

Immunogen: Fusion protein of human PPP1R1A

Swissprot: Q13522
Gene Accession: BC022470

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.02 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.