PPP1R3C Polyclonal Antibody

Background:
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
OTTHUMP00000020089, Phosphatase 1, regulatory inhibitor subunit 5, PP1 subunit R5, ppp1r3c, PPP1R5 , PPR3C, Protein phosphatase 1 regulatory subunit 3C, Protein phosphatase 1 regulatory subunit 5, protein phosphatase 1, regulatory (inhibitor) subunit 3C, Protein targeting to glycogen, PTG, R5

Immunogen: Fusion protein of human PPP1R3C

Swissprot: Q9UQK1
Gene Accession: BC012625

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.