PPP1R8 polyclonal, anti-human, mouse, rat

Background:
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Synonyms: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047

Cellular Location: Cytoplasm Nucleus Nucleus speckle

Immunogen:
Recombinant protein of human PPP1R8

Gene Symbol: PPP1R8

Gene ID: 5511

Swiss prot: Q12972

Calculated MW: 38kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.