PPP2R1A polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7866
Background:
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aα and PP2Aβ. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-α and -A-β, PP2A-B-α and -B-β, PP2A-C-α and -C-β, PP2A-B56-α and -B56-β.
Alternative Name:
Alpha isoform of regulatory subunit A, protein phosphatase, DKFZp470L0914, Medium tumor antigen-associated 61 kDa protein, MGC128399, MGC786, MGC83000, MGC95083, PP2A Aalpha, PP2A, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PP2A, subunit A, PR65-alpha isoform, PP2A, subunit A, R1-alpha isoform, PP2AAALPHA, Ppp2r1a, ppp2r1a-b, PR65, PR65-alpha, PR65A, Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform, isoform CRA_a, Protein phosphatase 2 (formerly 2A), regulatory subunit A, , Protein phosphatase 2 regulatory subunit A alpha, Protein phosphatase 2, 65-KD regulatory subunit A, alpha, Protein phosphatase 2, regulatory subunit A, alpha isoform, Protein phosphatase 2, structural/regulatory subunit A, alpha, PPP2R1A, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PPP2R1A polyclonal antibody detects endogenous levels of PPP2R1A protein.
Immunogen:
Recombinant full length Human PPP2R1A.
MW: ~ 65 kDa
Swis Prot.: P30153
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aα and PP2Aβ. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-α and -A-β, PP2A-B-α and -B-β, PP2A-C-α and -C-β, PP2A-B56-α and -B56-β.
Alternative Name:
Alpha isoform of regulatory subunit A, protein phosphatase, DKFZp470L0914, Medium tumor antigen-associated 61 kDa protein, MGC128399, MGC786, MGC83000, MGC95083, PP2A Aalpha, PP2A, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PP2A, subunit A, PR65-alpha isoform, PP2A, subunit A, R1-alpha isoform, PP2AAALPHA, Ppp2r1a, ppp2r1a-b, PR65, PR65-alpha, PR65A, Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform, isoform CRA_a, Protein phosphatase 2 (formerly 2A), regulatory subunit A, , Protein phosphatase 2 regulatory subunit A alpha, Protein phosphatase 2, 65-KD regulatory subunit A, alpha, Protein phosphatase 2, regulatory subunit A, alpha isoform, Protein phosphatase 2, structural/regulatory subunit A, alpha, PPP2R1A, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PPP2R1A polyclonal antibody detects endogenous levels of PPP2R1A protein.
Immunogen:
Recombinant full length Human PPP2R1A.
MW: ~ 65 kDa
Swis Prot.: P30153
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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