PPP2R1A Polyclonal Antibody

Background:
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Research Area: Cancer, Signal transduction

Synonyms:
PPP2R1A, MRD36, PP2A-Aalpha, PP2AA, PP2AAALPHA, PR65A

Immunogen: Recombinant fusion protein of human PPP2R1A (NP_055040.2).

Swissprot: P30153
Gene ID: 5518

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.