PPP2R1B polyclonal, anti-human, mouse, rat

Background:
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Synonyms: PP2A-Abeta, PR65B

Cellular Location: secreted

Immunogen:
Recombinant protein of human PPP2R1B

Gene Symbol: PPP2R1B

Gene ID: 5519

Swiss prot: P30154

Calculated MW: 66kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.