PPP2R4 (clone 4D9), anti-human

Background:
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Signal transduction

Synonyms: PP2A, PR53, PTPA

Immunogen: Purified recombinant fragment of human PPP2R4 expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage