PPP2R4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7316
Background:
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name:
subunit B'', KIAA0044, MGC2184, Phosphotyrosyl phosphatase activator, PP2A, PP2A phosphatase activator, PP2A subunit B', PP2A subunit B' isoform PR53, PP2A subunit B' PR53 isoform, PPP2R4, PR53, PR53 isoform, Protein phosphatase 2, regulatory subunit B-prime, Protein phosphatase 2A activator regulatory subunit 4, Protein phosphatase 2A regulatory subunit B' (PR 53), PTPA, PTPA_HUMAN, Serine/threonine protein phosphatase 2A regulatory subunit B', Serine/threonine-protein phosphatase 2A activator, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B'',
Application Dilution: IHC: 1:50 - 1:200, IF: 1:50 - 1:200
Specificity: PPP2R4 polyclonal antibody detects endogenous levels of PPP2R4 protein.
Immunogen:
Recombinant full length Human PPP2R4.
MW: ~40 kDa
Swis Prot.: Q15257
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name:
subunit B'', KIAA0044, MGC2184, Phosphotyrosyl phosphatase activator, PP2A, PP2A phosphatase activator, PP2A subunit B', PP2A subunit B' isoform PR53, PP2A subunit B' PR53 isoform, PPP2R4, PR53, PR53 isoform, Protein phosphatase 2, regulatory subunit B-prime, Protein phosphatase 2A activator regulatory subunit 4, Protein phosphatase 2A regulatory subunit B' (PR 53), PTPA, PTPA_HUMAN, Serine/threonine protein phosphatase 2A regulatory subunit B', Serine/threonine-protein phosphatase 2A activator, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B'',
Application Dilution: IHC: 1:50 - 1:200, IF: 1:50 - 1:200
Specificity: PPP2R4 polyclonal antibody detects endogenous levels of PPP2R4 protein.
Immunogen:
Recombinant full length Human PPP2R4.
MW: ~40 kDa
Swis Prot.: Q15257
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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