PPP2R5C Polyclonal Antibody

Background:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
PPP2R5C, B56G, PR61G, B56gamma

Immunogen: Recombinant fusion protein of human PPP2R5C (NP_848702.1).

Swissprot: Q13362
Gene ID: 5527

Calculated MW: 52 kDa/56 kDa/61 kDa/62 kDa/64 kDa
Observed MW: 68-71 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.