PPP3CA polyclonal, anti-human, mouse, rat

Background:
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A, PP2B-A∫ and PP2B-A. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

Synonyms: CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B

Cellular Location: Cell membrane Nucleus sarcolemma

Immunogen:
Recombinant protein of human PPP3CA

Gene Symbol: PPP3CA

Gene ID: 5530

Swiss prot: Q08209

Calculated MW: 59kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.