PPP3CC Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12168a
Background:
Calmodulin-dependent protein phosphatase, calcineurin, isinvolved in a wide range of biologic activities, acting as aCa(2+)-dependent modifier of phosphorylation status. In testis, themotility of the sperm is thought to be controlled by cAMP-dependentphosphorylation and a unique form of calcineurin appears to beassociated with the flagellum. The calcineurin holoenzyme iscomposed of catalytic and regulatory subunits of 60 and 18 kD,respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurinA-gamma (CALNA3), have been cloned for the catalytic subunit. Thesegenes have been identified in humans, mice, and rats, and arehighly conserved between species (90 to 95% amino acididentity).
Other Names:
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, PPP3CC, CALNA3, CNA3
Gene Name: PPP3CC
Gene ID: 5533
Primary Accession: P48454
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Calmodulin-dependent protein phosphatase, calcineurin, isinvolved in a wide range of biologic activities, acting as aCa(2+)-dependent modifier of phosphorylation status. In testis, themotility of the sperm is thought to be controlled by cAMP-dependentphosphorylation and a unique form of calcineurin appears to beassociated with the flagellum. The calcineurin holoenzyme iscomposed of catalytic and regulatory subunits of 60 and 18 kD,respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurinA-gamma (CALNA3), have been cloned for the catalytic subunit. Thesegenes have been identified in humans, mice, and rats, and arehighly conserved between species (90 to 95% amino acididentity).
Other Names:
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, PPP3CC, CALNA3, CNA3
Gene Name: PPP3CC
Gene ID: 5533
Primary Accession: P48454
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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