PPP4C (clone 2F11-D10-G4), anti-human antibody
€295.00
In stock
SKU
AC-ABV12074-100
Catalog Number: AC-ABV12074-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IF
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB, IF
Datasheet
Request Information
Background:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair.
Other Names:
Pp4, Protein phosphatase X, PP-X, PPP4C, PPP4, PPX
Primary Accession: P60510
Gene Name: PPP4C
Gene ID: 5531
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair.
Other Names:
Pp4, Protein phosphatase X, PP-X, PPP4C, PPP4, PPX
Primary Accession: P60510
Gene Name: PPP4C
Gene ID: 5531
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