PPP4C polyclonal, anti-human, mouse, rat

Background:
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Synonyms: PP-X, PP4, PP4C, PPH3, PPP4, PPX

Cellular Location: Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center

Immunogen:
Recombinant protein of human PPP4C

Gene Symbol: PPP4C

Gene ID: 5531

Swiss prot: P60510

Calculated MW: 35kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100, IP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.