PPP4R2 polyclonal (Center), anti-human, mouse
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In stock
SKU
AC-AP18485c
Catalog Number: AC-AP18485c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37606
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37606
Applications: WB
Datasheet
Request Information
Background:
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Other Names:
Serine/threonine-protein phosphatase 4 regulatory subunit 2, PPP4R2
Target/Specificity:
This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.
Antigen Region:
228-254
Antigen Type: Synthetic Peptide
Gene Name: PPP4R2
Gene ID: 151987
Primary Accession: Q9NY27
NCBI Accession: NP_777567.1
Other Accession: NP_777567.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Other Names:
Serine/threonine-protein phosphatase 4 regulatory subunit 2, PPP4R2
Target/Specificity:
This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.
Antigen Region:
228-254
Antigen Type: Synthetic Peptide
Gene Name: PPP4R2
Gene ID: 151987
Primary Accession: Q9NY27
NCBI Accession: NP_777567.1
Other Accession: NP_777567.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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