PR (clone 2F12B4,2F12H2), anti-human
€421.00
In stock
SKU
252684
Protein Family: Receptors and Channels, Transcription Factors
Pathway and Disease: Cancers, Cell Growth and Death, Signaling Molecules and Interaction, Transcription
Description:
PR (Progesterone receptor) is a transcription factor that is regulated by the binding of their cognate ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors.
Alternate Names: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P06401
Antigen: Purified recombinant fragment of PR expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Growth and Death, Signaling Molecules and Interaction, Transcription
Description:
PR (Progesterone receptor) is a transcription factor that is regulated by the binding of their cognate ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors.
Alternate Names: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P06401
Antigen: Purified recombinant fragment of PR expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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