PR polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels, Transcription Factors

Pathway and Disease: Cancers, Cell Growth and Death, Signaling Molecules and Interaction, Transcription

Description:
The progesterone receptor (PR) is a transcription factor that is regulated by the binding of their cognate ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors.

Alternate Names: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: P06401

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PR.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.