PRAME polyclonal, anti-human

Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The encoded protein acts as a repressor of retinoic acid receptor and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Synonyms: CT130, MAPE, OIP-4, OIP4

Cellular Location: Cell membrane Nucleus

Immunogen:
Recombinant protein of human PRAME

Gene Symbol: PRAME

Gene ID: 23532

Swiss prot: P78395

Calculated MW: 58kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.