PRAME polyclonal, anti-human

Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Synonyms: MAPE, OIP4, CT130, OIP-4

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human PRAME

Gene Symbol: PRAME

Gene ID: 23532

Swiss prot: P78395

Calculated MW: 58kDa

Recommended dilution:
IHC 1:10-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.