PRDM14 Blocking Peptide (N-term)

Background:
Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'.

Other Names:
PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14

Target/Specificity:
The synthetic peptide sequence is selected from aa 128-143 of HUMAN PRDM14

Gene Name: PRDM14

Gene ID: 63978
Primary Accession: Q9GZV8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.