PRDM14 (PFM11) Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1214b
Background:
Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family.PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.
Other Names:
PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1214b was selected from the PFM11 region of human PRDM14 (PFM11) . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRDM14
Gene ID: 63978
Primary Accession: Q9GZV8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family.PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.
Other Names:
PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1214b was selected from the PFM11 region of human PRDM14 (PFM11) . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRDM14
Gene ID: 63978
Primary Accession: Q9GZV8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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