PRDM14 polyclonal (N-term), anti-human

PRDM14 polyclonal (N-term), anti-human

€0.00
In stock
SKU
AC-AP21051a
Catalog Number: AC-AP21051a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51369
Applications: WB
Datasheet

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Background:
Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'.

Other Names:
PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14

Target/Specificity:
This PRDM14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-163 amino acids from the N-terminal region of human PRDM14.

Gene Name: PRDM14
Gene ID: 63978
Primary Accession: Q9GZV8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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