PRDX1 Monoclonal Antibody

Background:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism

Synonyms:
Heme binding 23 kDa protein, MSP23, Natural killer cell-enhancing factor A, NKEF A, NKEF-A, NKEFA, OSF3, Osteoblast specific factor 3, PAG, Paga, PAGB, Peroxiredoxin-1, PRDX1, PRDX1, Proliferation associated gene A, Proliferation-associated gene protein, PRX1, PrxI, TDPX2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2

Immunogen: Recombinant Protein

Swissprot: Q06830
Observed MW: 21 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.