PRDX3 antibody (clone 1E3-B2), anti-human
€435.00
In stock
SKU
AC-AT3422a
Catalog Number: AC-AT3422a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, IP, E
Request Information AC-AT3422a">Request Information
Background:
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
Antigen Type:
Recombinant Protein
Gene Name: PRDX3
Gene ID: 10935
NCBI Accession: NP_006784.1;NP_054817.2
Primary Accession: P30048
Other Accession: BC002685
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
Antigen Type:
Recombinant Protein
Gene Name: PRDX3
Gene ID: 10935
NCBI Accession: NP_006784.1;NP_054817.2
Primary Accession: P30048
Other Accession: BC002685
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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