PRDX3 Polyclonal Antibody

Background:
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms:
Antioxidant protein 1, AOP 1, AOP-1, AOP1, HBC189, MER5, MGC104387, MGC24293, mitochondrial, peroxiredoxin 3, Peroxiredoxin III, Peroxiredoxin-3, PRDX3, PRDX3, PRO1748, Protein MER5 homolog, PRX III, Prx-III, PRX3, SP 22, SP-22, SP22, Thioredoxin dependent peroxide reductase mitochondrial, Thioredoxin-dependent peroxide reductase

Immunogen: Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein

Swissprot: P30048

Calculated MW: 28 kDa
Observed MW: 28 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.