Prealbumin, PA (clone F28), anti-human
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In stock
SKU
BMA1037
Catalog Number: BMA1037
Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB
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Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB
Request Information
Background:
Prealbumin (PA), as known as Transthyretin (TTR), is an evolutionarily conserved serum and cerebrospinal fluid (CSF) protein that transports holo-retinol-binding protein (RBP) and thyroxine (T4). It is a 62-kDa homotetramer with a dimer of dimers quaternary structure that is synthesized mainly in liver, choroid plexus, retinal pigment epithelium for secretion into the bloodstream, cerebrospinal fluid and the eye, respectively. It maintains normal levels of retinol, retinol-binding protein, and thyroid hormone in the circulating plasma.[1]TTR misfolding and aggregation is known to be associated with the amyloid diseases[2]senile systemic amyloidosis (SSA),[3]familial amyloid polyneuropathy (FAP),[4]and familial amyloid cardiomyopathy (FAC).[5]
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the region of human PA.
Recommended Application:
Western Blot, WB(1:1000-2000)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Prealbumin (PA), as known as Transthyretin (TTR), is an evolutionarily conserved serum and cerebrospinal fluid (CSF) protein that transports holo-retinol-binding protein (RBP) and thyroxine (T4). It is a 62-kDa homotetramer with a dimer of dimers quaternary structure that is synthesized mainly in liver, choroid plexus, retinal pigment epithelium for secretion into the bloodstream, cerebrospinal fluid and the eye, respectively. It maintains normal levels of retinol, retinol-binding protein, and thyroid hormone in the circulating plasma.[1]TTR misfolding and aggregation is known to be associated with the amyloid diseases[2]senile systemic amyloidosis (SSA),[3]familial amyloid polyneuropathy (FAP),[4]and familial amyloid cardiomyopathy (FAC).[5]
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the region of human PA.
Recommended Application:
Western Blot, WB(1:1000-2000)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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