Prealbumin polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

Description:
Rabbit IgG polyclonal antibody for Transthyretin (TTR) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
Amyloid polyneuropathy antibody, Amyloidosis I antibody, ATTR antibody, Carpal tunnel syndrome 1 antibody, CTS antibody, CTS1 antibody, Dysprealbuminemic euthyroidal hyperthyroxinemia antibody, Dystransthyretinemic hyperthyroxinemia antibody, Epididymis luminal protein 111 antibody, HEL111 antibody, HsT2651 antibody, PALB antibody, Prealbumin amyloidosis type I antibody, Prealbumin antibody, Prealbumin Thyroxine-binding antibody, Senile systemic amyloidosis antibody, TBPA antibody, Thyroxine binding prealbumin antibody, Transthyretin antibody, TTHY_HUMAN antibody, TTR antibody, TTR protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse Prealbumin recombinant protein (Position: G21-N147). Mouse Prealbumin shares 81% and 94.5% amino acid (aa) sequence identity with human and rat Prealbumin, respectively.E.coli-derived mouse Prealbumin recombinant protein (Position: G21-N147). Mouse Prealbumin shares 81% and 94.5% amino acid (aa) sequence identity with human and rat Prealbumin, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.