Prealbumin Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes transthyretin| one of the three prealbumins including alpha-1-antitrypsin| transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid| and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition| affecting predominantly peripheral nerve and/or the heart| and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy| euthyroid hyperthyroxinaemia| amyloidotic vitreous opacities| cardiomyopathy| oculoleptomeningeal amyloidosis| meningocerebrovascular amyloidosis| carpal tunnel syndrome| etc.

Research Area: Neuroscience, Cardiovascular

Synonyms: Prealbumin, Transthyretin, ATTR, Prealbumin, TBPA

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year