PRELP Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6665b
Background:
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Other Names:
Prolargin, Proline-arginine-rich end leucine-rich repeat protein, PRELP, SLRR2A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6665b was selected from the C-term region of human PRELP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRELP
Gene ID: 5549
Primary Accession: P51888
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Other Names:
Prolargin, Proline-arginine-rich end leucine-rich repeat protein, PRELP, SLRR2A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6665b was selected from the C-term region of human PRELP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRELP
Gene ID: 5549
Primary Accession: P51888
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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