PRELP polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6665b
Catalog Number: AC-AP6665b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18591
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18591
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Other Names:
Prolargin, Proline-arginine-rich end leucine-rich repeat protein, PRELP, SLRR2A
Target/Specificity:
This PRELP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human PRELP.
Antigen Region:
257-286
Antigen Type: Synthetic Peptide
Gene Name: PRELP
Gene ID: 5549
Primary Accession: P51888
NCBI Accession: NP_002716.1;NP_958505.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Other Names:
Prolargin, Proline-arginine-rich end leucine-rich repeat protein, PRELP, SLRR2A
Target/Specificity:
This PRELP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human PRELP.
Antigen Region:
257-286
Antigen Type: Synthetic Peptide
Gene Name: PRELP
Gene ID: 5549
Primary Accession: P51888
NCBI Accession: NP_002716.1;NP_958505.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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