Presenilin 1 polyclonal, anti-human, mouse, rat antibody

Presenilin 1 polyclonal, anti-human, mouse, rat antibody

€295.00
In stock
SKU
AC-ABV10350-100
Catalog Number: AC-ABV10350-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet

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Background:
Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning thro µgh its associated g-secretase activity for amyloid-β protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments.

Other Names:
PSEN1, Presenilin-1, PS-1, Protein S182, Presenilin-1 NTF subunit, Presenilin-1 CTF subunit, Presenilin-1 CTF12, PS1-CTF12

Primary Accession: P49768

Gene Name: PSEN1

Gene ID: 5663

Concentration (mg/ml): 0.5 mg/ml
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