Presenilin 2 polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10351-100
Catalog Number: AC-ABV10351-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning thro µgh its associated g-secretase activity for amyloid-β protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments.
Other Names:
PSEN1
Primary Accession: P49810
Other Accession: NP_036618
Gene Name: PSEN2
Gene ID: 5664
Concentration (mg/ml): 0.5 mg/ml
Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning thro µgh its associated g-secretase activity for amyloid-β protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments.
Other Names:
PSEN1
Primary Accession: P49810
Other Accession: NP_036618
Gene Name: PSEN2
Gene ID: 5664
Concentration (mg/ml): 0.5 mg/ml
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