PREX1 polyclonal, anti-human

Background:
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

Other Names:
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,4,5)-dependent Rac exchanger 1, PREX1, KIAA1415

Antigen Types:
Synthetic Peptide

Gene Name:
PREX1
Gene ID:
57580
Primary Accession: Q8TCU6
Other Accession: NP_065871;57580;277360 (mouse); 311647 (rat);