PREX1 polyclonal (C-term), anti-human

PREX1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP12575b
Catalog Number: AC-AP12575b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31307
Applications: WB, IHC-P, FC
Datasheet

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Background:
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

Other Names:
Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,5)-dependent Rac exchanger 1, PREX1, KIAA1415

Target/Specificity:
This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1.

Antigen Region:
1134-1163

Antigen Type: Synthetic Peptide

Gene Name: PREX1
Gene ID: 57580
Primary Accession: Q8TCU6
NCBI Accession: NP_065871.2
Other Accession: NP_065871.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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