PRIM1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008],function:DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.,miscellaneous:The bound zinc ion is not a cofactor. It is bound to a zinc knuckle motif that may be involved in sequence recognition and the binding of ssDNA.,similarity:Belongs to the eukaryotic-type primase small subunit family.,subunit:Heterodimer of a small subunit and a large subunit.,

Synonyms: PRIM1, DNA primase small subunit, DNA primase 49 kDa subunit, p49

Gene Name: PRIM1

Gene ID: 5557

SwissProt ID: P49642

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.