PRKAA1 antibody (clone 4D8), anti-human
€435.00
In stock
SKU
AC-AT3426a
Catalog Number: AC-AT3426a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF
Request Information AC-AT3426a">Request Information
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Other Names:
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Antigen Type:
Recombinant Protein
Gene Name: PRKAA1 (HGNC:9376)
Gene ID: 5562
NCBI Accession: NP_006242.5;NP_996790.3
Primary Accession: Q13131
Other Accession: NM_006251
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Other Names:
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Antigen Type:
Recombinant Protein
Gene Name: PRKAA1 (HGNC:9376)
Gene ID: 5562
NCBI Accession: NP_006242.5;NP_996790.3
Primary Accession: Q13131
Other Accession: NM_006251
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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