PRKAA1 monoclonal, anti-human

PRKAA1 monoclonal, anti-human

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In stock
SKU
AC-AM1858b
Catalog Number: AC-AM1858b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,K
Clone Name: 167CT22.1.6
Applications: WB
Datasheet

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Background:
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

Other Names:
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1

Target/Specificity:
This PRKAA1 monoclonal antibody is generated from mouse immunized with PRKAA1 recombinant protein.

Antigen Type: Recombinant Protein

Gene Name: PRKAA1 (HGNC:9376)
Gene ID: 5562
Primary Accession: Q13131
NCBI Accession: NP_006242.5;NP_996790.3
Other Accession: P54645; NP_006242.5
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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