PRKAA2 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1887b
Catalog Number: AC-AM1887b
Size: 80 µl, 400 µl
Isotype: mouse IgG2a,K
Clone Name: 206CT5.4.2
Applications: WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG2a,K
Clone Name: 206CT5.4.2
Applications: WB, IF
Datasheet
Request Information
Background:
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Other Names:
5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Target/Specificity:
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: PRKAA2 (HGNC:9377)
Gene ID: 5563
Primary Accession: P54646
NCBI Accession: NP_006243.2
Other Accession: NP_006243.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Other Names:
5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Target/Specificity:
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: PRKAA2 (HGNC:9377)
Gene ID: 5563
Primary Accession: P54646
NCBI Accession: NP_006243.2
Other Accession: NP_006243.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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