PRKAB2 antibody (clone 2G9), anti-human
€435.00
In stock
SKU
AC-AT3429a
Catalog Number: AC-AT3429a
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, E
Request Information AC-AT3429a">Request Information
Background:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.
Other Names:
5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2, PRKAB2
Antigen Type:
Recombinant Protein
Gene Name: PRKAB2
Gene ID: 5565
NCBI Accession: NP_005390.1
Primary Accession: O43741
Other Accession: BC053610
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.
Other Names:
5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2, PRKAB2
Antigen Type:
Recombinant Protein
Gene Name: PRKAB2
Gene ID: 5565
NCBI Accession: NP_005390.1
Primary Accession: O43741
Other Accession: BC053610
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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