PRKAR1B polyclonal, anti-human, mouse, rat

Background:
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.

Synonyms: PRKAR1

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human PRKAR1B

Gene Symbol: PRKAR1B

Gene ID: 5575

Swiss prot: P31321

Calculated MW: 43kDa

Recommended dilution:
WB 1:1000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.