PRMT1 (clone 4E9-H9-H12), anti-human

Background:
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family.Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes,whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms.The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,and a pseudogene of this gene is located on the long arm of chromosome 5.[provided by RefSeq,Dec 2011]

Synonyms: ANM1, HCP1, HRMT1L2, IR1B4

Cellular Location: Cytoplasm Nucleus cytosol nucleoplasm

Immunogen:
Purified recombinant human PRMT1 protein fragments expressed in E.coli.

Gene Symbol: PRMT1

Gene ID: 3276

Swiss prot: Q99873

Calculated MW: 42kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.